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Patient Section


    • Why would I prefer Xytex rather than another reproductive tissue bank?

      Xytex is about people and creating families. Our specialists want patients to receive the best possible match to a Xytex donor. We have a large variety of donors and extensive information about each one. Xytex is also steeped in medical heritage with a strong clinical component. Donor units are released from inventory for use only by physician review and approval of technical specifications; it is similar to obtaining a prescription drug.

    • What qualifies Xytex to be a gamete provider?

      Xytex is an international organization of health care professionals dedicated to helping physicians and their patients find a donor suitable to the needs of individual patients. Being international, Xytex has access to the world's best medical authorities and has selected a few of these to form the Xytex Medical Advisory Board. Xytex is sensitive to cultural and ethical issues of patients and has a diverse group of donors.

      Xytex began providing male gametes in 1975 from Augusta, Georgia. This service originated from clinical research at the Medical College of Georgia in Augusta, one of the world's premiere academic centers for reproductive medicine.

      More than a professional and ethical responsibility, the quality of Xytex's clinical services is validated by state and national governmental agencies with authority to shutdown non-compliant programs. This authoritative oversight is enhanced by voluntary programs of peer review. Xytex, as part of its professional responsibilities, encourages its staff to participate in the activities of the American Association of Bioanalysts, the American Association of Tissue Banks, the American Society for Reproductive Medicine, the Canadian Fertility and Andrology Society and the European Society for Human Reproduction and Embryology. Xytex is proud that the quality management system governing the manufacture of our products is ISO 9001:2008 certified.

    • What accreditation or licenses does Xytex have?

      To view a current list of licenses, registrations and certifications, please visit our Licenses and Accreditations page. 

      Xytex also adheres to the regulations regarding importation of its products by the governments of Switzerland, Australia, and the United Kingdom (HFEA) as well as Health Canada, a federal governing board of Canada.

      Xytex operates by the International Organization for Standardization (ISO), a worldwide federation of national standards bodies that works to facilitate international trade by providing a single set of recognized and agreed upon standards that people everywhere understand and respect.  This applies to medical organizations, including the College of American Pathologists, and to government organizations, including the Centers for Disease Control and Prevention. The quality management system governing the manufacture of Xytex products is ISO 9001:2008 certified. Certification provides objective proof that Xytex has implemented an effective quality management system, satisfying all of the requirements of the ISO 9001:2008 standard. Xytex’s quality management system enables Xytex to evaluate operational effectiveness, increase efficiency and enhance user satisfaction, as well as identify areas for improvement.  With auditing and monitoring criteria in place, the company focuses on continuous improvement methodologies to enhance its program.

    • How do you ensure my confidentiality as a Xytex user?

      Reproduction is a very personal matter and we respect your desire for privacy. The information you share with us is held in strictest confidence, unavailable to anyone other than your health care professionals without your express permission. Your information will not be shared or sold to any other company or institution. Likewise, Xytex respects donor privacy and releases information about the donors only with the donor's permission.  Encryption of your financial information is provided through Authorize.net.

    • How do I get started in selecting a semen donor?

      We require a woman to be under the care of a physician before units are shipped. Your doctor can advise the type of procedure and the type of units needed. The required type of vial(s) depends on the type of treatment. If you do not have a health care professional that specializes in artificial insemination, you may contact our team who can help you select one in your area.

      Once you have selected your inseminating health care professional and have narrowed your donor choices, please contact us at 1-706-733-0130 to help you with your order.

    • What should I do before I call to place an order?

      Select several donors who possess the characteristics you seek, and rank them in your order of preference. Call Xytex to check availability of these donors. Xytex will make every effort to secure your first-choice donor, but due to normal fluctuations in our inventory, this is not always possible. We recommend ordering as early as you can to improve your chances of getting your first choice. You may also order units for future use by placing them on reserve. Pre-purchasing units guarantees that they will be there when you need them.

      There are other technical factors to decide before ordering. The expected day of your ovulation must be determined in order to schedule shipment, as well as the number and type of insemination units needed. The volume of one Xytex unit contains 0.5 milliliter. You also need to know whether you will need washed units suitable for intrauterine insemination), unwashed units (for intracervical inseminations or procedures requiring further processing by your team), or ART or ICSI units (suitable for use in procedures such as IVF and ICSI). Plan to have your order delivered a day or two in advance of ovulation.

    • Where is Xytex located?

      Xytex is headquartered in Augusta, GA with locations in Atlanta, Georgia and New Brunswick, New Jersey. 

      Corporate Office

      1100 Emmett Street
      Augusta, Georgia 30904-5826
      United States of America

      Atlanta Office

      730 Peachtree Street NE, Suite 675
      Atlanta, GA 30308
      United States of America

      New Jersey Office

      303 George Street, Suite G30
      New Brunswick, New Jersey 08901


    • What kind of men are Xytex donors?

      Xytex recruits men (age 18-38) throughout the community, especially at colleges because students seem to be the most interested in donation opportunities.  However, even professionals with advanced degrees such as law, medicine, and science participate in the Xytex donor program.  Some are married with children of their own.

    • Are Xytex donors altruistic?

      Many Xytex donors are altruistic in the sense that they deeply care about the consequences of semen donation, that they are helping others to have children. The question, however, usually is an inquiry as to whether donors receive incentives or monetary compensation for semen itself.  Actually, donors must do much more than simply provide semen. Donors must fill out lengthy questionnaires, research their family medical histories, endure frequent physical examinations, blood draws and even adopt a lifestyle consistent with clinical requirements. Yes, Xytex compensates its semen donors.

    • Are Xytex donors anonymous?

      In reality, Xytex has a spectrum of semen donors, almost all of whom are anonymous at the time the recipient is inseminated. The few donors that are non-anonymous are those that are individually arranged by the client and Xytex Tissue Storage Inc., not Xytex.  Only anonymous donors are presented here, listed on the Xytex panel, and available for general distribution. All of these anonymous donors give up all rights to children from their donor semen, but they expect their privacy to be honored. Yes, many of them are willing to provide a lot of personal descriptive information, but none have agreed to directly, personally communicate with recipients of their semen. Please note that a donor participating in the Xytex Identity Disclosure program allows Xytex to release his identity to his offspring at age 18 and older.

    • What is an Identity Disclosure Donor?

      Some Xytex donors volunteer to disclose their identities to children conceived with their sperm once the children reach 18 years of age. To be eligible to receive this information a child's mother, recipient of the sperm, must sign an agreement and report the child's birth to Xytex. These requirements ensure that Xytex can verify the child's eligibility to receive such information in the future. Identity Disclosure Donors have agreed to allow Xytex to release their identities but have not made any commitment beyond this. Xytex will disclose this information upon the request of a properly registered child who is 18 years of age or older. Upon request of the child, for a nominal fee, Xytex will assist in the search for the donor. Xytex cannot guarantee the child's or its own success in locating the donor and cannot guarantee the child personal contact with the donor. While a donor's participation in this program indicates a certain openness to contact it is not a guarantee of contact. It is important that recipients and their children understand this and set realistic expectations.

      Please refer to the Recipient Agreement for more details about our Identity Disclosure Donor Program.

    • What information is available on Xytex donors?

      In addition to the conventional donor list and written profiles (donor’s psychosocial preferences, donor’s medical history, family genetic history), many donors provide both childhood and adult photos, Identity Disclosure, live audio interviews, and a personality evaluation in the form of the Keirsey Temperament Sorter. Please note, not all options are available for all donors.

    • How does the Xytex “Basic Profile” differ from the “Enhanced Profile”?

      The Basic Profile is extremely comprehensive and provides our clients with a donor’s responses to our "Basic Profile," including personal and family medical histories, the donor’s education level, his occupation and physical attributes, among other things. The Basic Profile is FREE. However, should a client find a donor of particular interest, an Enhanced Profile is available for a nominal fee. The Enhanced Profile provides the client with the Basic Profile information as well as baby and adult photos, if available; a donor essay; a personality evaluation in the form of the Kerisey Temperament Sorter, and other personality attributes of the donor. 

    • How often does Xytex update its donor list on the Web?

      Xytex updates donor listings as changes occur.  This process includes new, previously unknown information about the donor -- everyone learns more about themselves throughout life.  The donor list on the Web is intended to post “who’s available for selection,” rather than to be an archive of all information on all Xytex donors.  It is our intent to list only “available” donors, but inventory on any donor can fluctuate drastically on a daily basis, so occasionally, a listed donor will actually be “unavailable.”  It is important to let a client services representative know your donor preferences so that you can be placed on the pending list for that particular donor; call us at 706-733-0130.

    • Does Xytex offer baby and adult photos of donors?

      Yes, Xytex offers baby photos and adult photos for most donors. You can search donors with available photos by using the advanced donor search feature and selecting "Only Donors with Donor Photos." 

    • Other sperm banks offer “premium” donors (for a higher fee); why doesn’t Xytex offer this option?

      Xytex maintains that ALL of our donors are “premium” donors. Regardless of the educational background, family heritage or current profession, every one of our donors has something special and unique to offer you and your family.

    • How important is choosing a donor with a specified blood type?

      That consideration is up to you. If you plan to tell your child about the use of a donor, the donor’s blood type is not as important as if you don’t anticipate telling your child. In order to avoid future questions, some couples wish to have a baby with a blood type that would be the same as a baby conceived by the husband. This concern should be discussed with your medical professional. More critically, blood type is medically important to women who are Rh-negative. These women may develop antibodies to a fetus that is Rh-positive. There is a 50 to 100 percent chance of having an Rh-positive fetus if the semen donor is Rh-positive. The importance of this possibility should be discussed with your health care professional. If the patient is Rh-positive and the husband’s blood type matching is not desired, then you can choose a donor without regard to blood type. This option greatly enhances your choice of donors.

    • What can Xytex tell me about the interaction of the donor’s genes with those I’ve gotten from my parents?

      Genetic factors can be an important part of the semen donor selection process. For more information on genetics and genetic testing, please visit our Frequently Asked Questions About Genetic Screening and Testing of Donors.

    • Does Xytex have birth limits that reduce the chance of half-siblings unknowingly conceiving a child together?

      Xytex shares your concern regarding the possibility of inadvertent consanguinity, that two persons conceived with sperm from the same donor might unknowingly conceive a child together. In the United States there are no laws or regulations regarding the number of children that can be conceived with sperm from a donor. The American Society for Reproductive Medicine (ASRM) suggests "that in a population of 800,000, limiting a single donor to no more than 25 births would avoid any significant increased risk of inadvertent consanguineous conception." This recommendation would permit nearly 10,000 children from a single donor in the United States.

      Xytex believes this is an unacceptably high number and has chosen a limit of 60 family units. General distribution of sperm from a donor is stopped once 60 families (worldwide) have reported births. Any additional sperm remaining in inventory for that donor will only be available to those families desiring to conceive additional children with that same donor. Xytex makes it easy to report your pregnancy or the birth of your child online. Your timely reporting helps Xytex maintain accurate birth records.

      The likelihood that two donor-conceived half-siblings would ever meet unknowingly is quite low. Xytex distributes semen worldwide, further reducing these chances. Most families disclose to children their donor-conceived origins and their Xytex donor's number. Many half-siblings and their families actively seek out one another, creating an extended family and maintaining open communication. Xytex supports these efforts and has developed xyConnects, an online forum that facilitates interaction among willing donor-conceived persons, their families, and their donors.

      Xytex believes that its birth limit and increasing openness regarding donor conception make it very unlikely that half-siblings would unknowingly meet and conceive a child together.

    • Will Xytex tell me whether a donor has enabled recipients to become pregnant?

      Yes, Xytex will share this information in a qualitative manner.  However, we do not disclose quantitative pregnancy rates because they are influenced by many factors beyond our control.  One is the number of times the donor has been selected; another is how his semen was thawed; another is the timing and method of insemination; then, there is the fertility of the recipient.

    • If a donor has no reported pregnancies is that necessarily a bad sign?

      No, that in no way indicates that a donor is not fertile. That could simply indicate that a donor has not been in the program for a very long time. Xytex performs rigorous testing to ensure that all of its donors provide high quality samples.


    • How does a man qualify to be a sperm donor for Xytex?

      Each Xytex donor is different, but all go through the same rigorous qualification procedure. This includes a thorough initial evaluation with periodic updates throughout the year. Before becoming a donor, a man is a donor candidate.

      A donor candidate must be between the ages of 18 and 38 and is interviewed extensively by a trained counselor to gain insight about his personality, behavior and health. He also provides a health history on up to four generations, including his own children, his siblings, parents, and grandparents. Since there is no legal way to obtain medical histories of family members, Xytex relies solely upon the donor for the accuracy of this information.

      A comprehensive physical exam is the next step for the suitable candidate. We screen for visible physical abnormalities and evidence of infectious disease, and collect samples of the candidate’s semen, urine, and blood for laboratory analysis. Our medical director reviews all of the medical information in a process that takes about two months to complete. The expertise of board certified clinical geneticists may be used to clarify special situations.

      Donors are evaluated through Medical History Updates, physical exams and lab testing at least twice a year, and most donors are screened and tested more frequently, depending upon inventory demand.  Information learned during re-evaluation deemed important to recipient or offspring is reported to the inseminating physician. A donor who remains in good health can continue to participate until they reach their 41st birthday, or until he reaches our limit of reported family units. Xytex screening and testing complies with government licensing agencies and is consistent with guidelines established by the FDA.

    • How often do you check donors for diseases? How long do you keep their records? What does Xytex do if it learns something important about my donor after I am inseminated?

      "Active" donors, that is, donors regularly providing samples of blood, semen and urine are screened and tested throughout the year.  These are permanent records at Xytex. Furthermore, we encourage donors to remain in contact with Xytex even when they "retire" from the donor program. When Xytex learns new information about a donor (either from the donor or from a recipient of his semen) that is deemed medically significant by the Medical Director, a notice is sent to the inseminating doctor and to any patient who used semen from the donor.

    • What diseases does Xytex check a donor for?

      Xytex screens or tests donors for the diseases listed in our “Basic Profile,” in our “Semen Donor Screening Guide”, and in our “Summary of Records”. The diseases are mainly infectious or genetic diseases that a donor could pass on to you or to your offspring. It is important for you to understand that the Xytex search for transmissible diseases is limited to those listed on the Donor Screening Guide. The list includes diseases required by governmental regulations. Even following these expectations, Xytex cannot guarantee that the donor is free of these diseases; all that can be said is that we have looked for them. This is a very technical matter that you may want to discuss with your health care professional.

    • When checking a donor for transmissible diseases, what is the difference between screening and testing?

      Screening looks for evidence, most commonly symptoms, of a particular infection. Testing involves applying laboratory methods to biologic specimens, such as blood, urine or semen, to determine the presence of a particular infectious agent, such as a bacteria or a virus. For example, the Food and Drug Administration (FDA) requires that semen banks screen donors for West Nile Virus (WNV) infection by asking whether the donor has recently experienced fever and headache or has been diagnosed with meningitis. When reliable, accurate tests become available, the FDA may require that semen banks test donors for WNV. In comparison, the FDA requires that semen banks test donors for HIV infection by looking for antibodies to the virus and the virus itself in a blood specimen.

    • What about diseases such as alcoholism, asthma, bipolar disorder, cancer, diabetes, heart disease, obesity, osteoporosis, psoriasis, stroke and all the others?

      Xytex screens or tests for diseases listed on the Semen Donor Screening Guide.  When a donor is in the first stages of qualification, he completes a Medical History Questionnaire.  His responses indicate whether he or any blood relative has ever been diagnosed with a lengthy list of diseases (genetic and infectious).  If he indicates that a family member has been diagnosed, this information is recorded and available in his basic profile. Each donor’s responses are reviewed by our medical director with assistance, when needed, by a geneticist.  Each donor is required to update this information every six months, information that is reviewed professionally.  Xytex urges anyone selecting a donor to have his Basic Profile reviewed by her physician.

    • Should I be concerned about having an allergic reaction to cryopreserved sperm?

      Xytex uses “Freezing Medium” produced by Irvine Scientific.  This is a media approved by the FDA for freezing semen for use in assisted reproductive procedures.  It is composed of a balanced salt solution, an antibiotic (gentamicin sulfate), glycerol, and heat-inactivated egg yolk.  Please consult your physician if you are allergic to gentamicin sulfate or egg yolk protein.

    • Why freeze sperm?

      Fresh semen is unsuitable for sperm banking because it begins losing its fertility within an hour or two after ejaculation.  Since a sperm bank is expected to have available at all times semen from a diversity of donors with different physical characteristics and different talents, it is necessary to bank or store the sperm from the time of collection until the time of need. Xytex accomplishes this by extending the survival period to years through a special freezing process of cryopreservation. It is the only way sperm can be shipped from the bank to a distant user. Also of great importance, sperm is cryopreserved to allow a quarantine period and the re-testing for sexually transmitted infections, such as HIV.  After being thawed, cryopreserved sperm can be just as fertile as "fresh" sperm.

    • What is the purpose of the quarantine period and how long does it last?

      Sperm is cryopreserved to allow for retesting of a variety of diseases, most importantly the HIV virus that causes the potentially-lethal AIDS infection. This means that freshly collected sperm must be stored for a minimum of six (6) months before repeat testing of the donor. Repeat testing includes HIV 1/2 + O antibodies, HTLV I & II antibodies, hepatitis B surface antigen, hepatitis B core antibody, hepatitis C, HIV/HCV/HBV NAT, RPR, TP-PA and cytomegalovirus (CMV) antibodies. Donors are also tested for Chlamydia and gonorrhea and receive a full genital (semen) culture.

    • Does “freezing” reduce the fertility of sperm?

      The cryopreserved sperm that Xytex provides is just as fertile, if not more fertile, than typical freshly ejaculated sperm. Cryopreservation requires careful selection of "freezable" donors, then adding materials to protect the cells from freezing injury, as well as regulating cooling and freezing in such a way to minimize freezing injury. The insemination material in IUI and ICI samples provided by Xytex has no fewer than 25 million motile sperm per milliliter, much "richer" than that provided by other sperm banks. A normal sperm count in a typical "fresh" ejaculate is 20 million sperm per milliliter. Because fewer cells are needed in procedures such as IVF and ICSI, Xytex ART vials have a guarantee of at least 10 million motile sperm per milliliter.

    • Does thawed semen cause more birth defects than normal?

      No. A comparison of human births resulting from thawed semen showed no difference in the rate of birth defects or miscarriage than in non-assisted pregnancies.

    • How long can human sperm survive cryopreservation?

      Scientists believe the potential for long-term storage is indefinite, assuming adequate maintenance of low temperature. In October 2005 the American Society for Reproductive Medicine published a report from four physicians that several women had normal births from semen stored for 28 years.


    • How can I be certain that Xytex will have sperm available from my favorite donor?

      The inventory of samples from a given donor changes on a daily basis as specimens are shipped from and added to our stock. Donors may also be "retired", or leave the program. If you have selected a donor and feel strongly about using him exclusively until you become pregnant -- or if you would like to have other children using the same donor -- you probably want to pre-purchase specimens to guarantee their availability when you need them. You or your physician may place a "reserve" order at any time by simply giving us a call. You pay for the samples, and we'll hold them for you in our facility. There is no storage fee for the first six months if you purchase six or more units; otherwise, a nominal monthly, biannual or annual storage fee applies. If you decide not to use your reserved specimens, or if you get pregnant quickly and don't need all of them, you'll receive a 50 percent refund on specimens cancelled within the first six months of your order. (Unfortunately, we are unable to make refunds on specimens reserved for more than six months of storage.)

    • How much sperm should be ordered?

      This is a technical question for your physician. Basically the question is whether to order one or more insemination units. An insemination unit is 0.5 milliliters and is usually enough for one insemination. Some physicians use a single unit during the fertile time and others use more. You should also be aware that Xytex provides no less than 25 million motile (swimming) sperm per milliliter for IUI and ICI and 10 million motile sperm per milliliter in an ART vial.

    • Are there other technical issues?

      Quite a few, actually: whether intracervical insemination (ICI), intrauterine insemination (IUI) units or ART vials are needed; whether an insemination appliance is needed; what date should the semen arrive. Again, consult your physician for answers appropriate to your situation.

    • What is the difference between “washed” and “unwashed” samples? Are some cleaner than others?

      The terms "washed" and "unwashed" can be confusing. However, these terms have nothing to do with the cleanliness of the semen. Washed units must be used if the patient is undergoing intrauterine insemination (IUI). Before cryopreservation, the sperm are separated from the seminal fluid and the fluid is replaced with a preservative fluid; this fluid replacement is the so-called "washing" process. It is critical that washed units are used in IUI as unwashed units injected into the uterus can cause violent cramping which, in addition to being extremely painful, will most likely result in the loss of all sperm injected. Both washed and unwashed samples can be used for ICI or intracervical inseminations. ART samples are processed in exactly the same way, the only difference being the minimum number of motile cells.

    • What comes in a shipment?

      Each unit of semen arrives frozen in a screw-cap vial. Each vial is clipped to a metal support rod (called a "cane") to facilitate vial removal from a refrigerated "tank" (or "dry shipper"). The tank is refrigerated with liquid nitrogen trapped in spongy material to prevent spillage, hence the name "dry shipper." The tank, documents and any other requested items are in a cardboard shipping box.  The documents include a packing slip with the Summary of Records (required by the FDA), thawing instructions and Medical Director letter, informed consent, a return shipping label and applicable invoices.

    • How do I place an order?

      You or your health care professional can place orders by calling Xytex at 706-733-0130, but shipments will only be sent to your medical specialist who has signed a Supply Agreement with Xytex (US physicians; International physicians). Orders placed by patients will be confirmed with the office that is to receive the shipment. An order placed before 3:00 p.m. Eastern Standard Time can be shipped the same day, otherwise, it will be shipped the following day. If you need a "rush" delivery or a weekend or holiday shipment, call our office and the answering service will help you contact the manager on call. We can usually arrange for a shipment to be delivered to your physician's office in less than 24 hours, although considerable additional charges will apply.

    • What types of shipping arrangements are available?

      Xytex will make all arrangements for your order to arrive at your professional's office on the guaranteed arrival date. You can choose a 24-hour or a two-day delivery option. Our shipping containers will keep your samples safely frozen for seven days, allowing for the unpredictable nature of ovulation. When you have used your specimen, Xytex will make all arrangements for the return of the shipping container.

    • If I live in the area can I come to Xytex and personally pick up my units?

      Yes, with proper identification you can come to our facility and retrieve your units. You can designate someone to pick up your order, but they must present a valid ID, as well. In addition, it also requires that you complete an authorization form signed by your physician. Click here to download the form.

    • Can I perform the insemination at home or can this only be done at the clinic?

      Xytex Corporation is willing to send your donor specimen to any address specified on your order form. Regardless of the destination of the shipment, Xytex requires its clients to be under a physician’s care. Your health care professional must sign an Authorization to Ship to an Alternate Location form prior to having any specimens shipped directly to the patient. Xytex recommends consulting with this professional on all matters relating to inseminations, including the decision to inseminate at home as there are serious risks to be considered.

    • I am interested in having and additional child with a retired donor; what steps do I take?

      This process is called “Donor Reactivation.”  It involves a step-by-step process that the Donor Counselor can go over with you.

    • What methods of payment do you accept?

      Xytex accepts payment by check, money order, cash and most major credit cards including VISA, MASTERCARD, AMERICAN EXPRESS, and DISCOVER cards.

    • If my doctor has semen I have purchased and do not need, will Xytex give me a refund if it is returned?

      No. Xytex does not restock semen that has left the warehouse. Xytex has full control over semen from the time the donor provides it until it leaves the warehouse. Once it leaves our facility, Xytex is no longer certain of its history, so in good faith, it cannot be offered to professionals and their patients as “Xytex semen”. However, Xytex can store this semen for your future use. There is a nominal storage fee.

    • If during insemination my M.D. feels the specimen is of poor quality; what do I do?

      Have your physician download and complete the Quality Report form. The report will be reviewed with the understanding that because labs are evaluating samples using several different counting chambers, we allow for up to a 20% variance from the total motile sperm cells listed on the packing slip.

      Ex: The guarantee is 12.5 million motile sperm per vial. With a 20% variance, 10.0 million motile sperm per vial is acceptable

      The Quality Report form must be received by Xytex within 30 days of thaw. Final decisions are made within 2 weeks. Only specimens that are thawed within 120 days of shipment to your physician’s office will be considered for replacements.

    • How do I report a birth?

      Please click here to report a birth. This information is very important to Xytex as it is used to track the number of births for each particular donor.

Do you have more questions? Please feel free to use the form below to contact us.

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