Since 1975, Xytex has provided guidance and expertise for those ready to start or grow their families. Our commitment to quality, transparency, and advanced donor screening helps intended parents make more informed and confident decisions.
Selective
Our donors are chosen with you and your future family in mind. All donors entering the program after 2017 must pass a rigorous screening process, including medical, psychological, and behavioral evaluations.
Tested
We evaluate all donors using comprehensive carrier screening covering hundreds of inherited conditions, as well as hereditary cancer genetic testing. Testing panels are regularly updated to reflect the latest advancements in genetics.
Transparent
Xytex prepares all vials with 0.5 milliliters of specimen, allowing you to clearly understand the number of motile sperm cells in each vial. While some banks use MOT as a concentration measurement per milliliter, Xytex provides clear vial-specific commitments for easier comparison and decision-making.
For example:
To view a current list of licenses, registrations and certifications, please visit our Licenses page.
We also adhere to the regulations regarding importation of products by the governments of Switzerland, Australia, and the United Kingdom (HFEA), as well as Health Canada, a federal governing board of Canada.
Your fertility journey is deeply personal, and we are committed to protecting your privacy. The information you share with us is held in the strictest confidence and is not shared with anyone, other than your healthcare provider, without your prior permission. We do not sell or provide your personal information to any third party, company, or institution.
We also respect donor privacy and only release donor information with the donor’s prior written consent. Client financial information is protected through secure, encrypted payment processing systems
A retired donor is no longer actively participating in the Xytex donor program and is no longer providing new donations. In some cases, remaining inventory may still be available for purchase. Donors may retire for a variety of personal reasons, and retirement does not necessarily reflect a change in the donor’s qualification status.
Selecting a sperm donor is a personal and sometimes complex decision, and we're here to support you throughout the process. Xytex strongly recommends consulting with your healthcare provider and a genetic counselor for individualized medical guidance as you make your selection.
To begin, create an account to access detailed donor profiles and additional selection tools. We suggest starting by identifying your key priorities—such as genetic screening, physical traits, education, or medical history—and using our search filters to help narrow your options.
If you have questions or would like more personalized support, we offer complimentary Zoom consultations with a member of our team.
Once you have selected your donor, you can place an order online or call us at 706-733-0130. Our team will be happy to guide you through the ordering process.
As of January 2019, Xytex no longer accepts anonymous donors into our donor program. All new donors are identity-disclosed. However, clients who have reported births from a previously accepted anonymous donor may still purchase vials from that donor’s remaining inventory, subject to availability.
We understand the importance of a child having the opportunity to learn more about their sperm donor. That’s why Xytex offers Identity Disclosure Donors—donors who have agreed to allow their identifying information (such as full name and last known contact details) to be shared with the donor-conceived individual once they turn 18.
To be eligible to receive this information, the child’s mother—the recipient of the donor sperm—must sign the Identity Disclosure Agreement and report the child’s birth to Xytex. These steps allow us to verify the child's eligibility and ensure accurate records are maintained for future disclosure.
While a donor’s participation in the Identity Disclosure Program reflects a willingness for transparency, it does not guarantee any form of contact or relationship. It simply permits the release of identifying information when the child becomes of age and requests it.
Our online donor database is regularly updated to reflect changes in donor status and inventory. While we aim to show donors with current availability, inventory levels can fluctuate due to ongoing demand.
If a donor you are interested in is currently unavailable, we encourage you to check back regularly, as inventory may be replenished. New donors are added frequently, providing a wide range of options to support your family-building journey.
In some cases, retired donors may still have limited inventory available. If so, this will be reflected on their profile.
Please note that Sibling-Only Donors—those reserved for families who have previously reported a birth—require a documented birth on file before additional vials can be purchased.
We require both child and adult photos for our donors. However, you may come across a few donors who joined the program before this requirement was implemented, thus only childhood photos may be available.
Genetic compatibility can be an important part of the donor selection process. Xytex provides detailed genetic screening information for each donor to help support informed decision-making. Because every individual’s genetic profile is unique, we strongly recommend consulting with your healthcare provider or a genetic counselor to better understand how a donor’s genetic background may interact with your own.
For more information about genetics and genetic testing, please view our Genetics FAQ
At Xytex, we take donor usage limits seriously to ensure ethical distribution and safeguard the well-being of donor-conceived individuals. Each donor's availability is limited based on both the length of time he remains in the program and the number and location of reported births.
We follow the recommendations of the American Society for Reproductive Medicine (ASRM). This guideline reflects Xytex’s commitment to supporting the long-term interests of donor-conceived people by helping to limit the number of families per donor. It aligns with industry standards and is part of our effort to promote responsible donor use across regions.
To comply with these standards, we:
monitor the geographic distribution of donor vials.
ask clients to report births so we can keep accurate records. Based on the factors listed above, access to a donor may be restricted for creating additional siblings.
Building a family looks different for everyone. Our donor options are designed to reflect your unique path and support the choices that matter most to you.
Exclusive Donors
These donors are available for purchase by a single Xytex family.
XYlimited Donors
With limited inventory and a set purchase requirement, these donors are available to fewer families.
Whether you're exploring donor options, planning for future siblings, or navigating next steps—our team is here to offer guidance, clarity, and support tailored to your family-building goals.
Yes, reported pregnancies are listed on each donor’s profile. However, Xytex does not provide pregnancy success rates, as many factors—such as insemination timing, method, thawing process, and recipient fertility—can affect outcomes and are beyond our control.
A donor without reported pregnancies is not necessarily infertile. This may simply indicate they are new to the program. All Xytex donors undergo rigorous screening, including laboratory testing and physical exams, and are regularly monitored to ensure the highest quality standards throughout their participation.
Colorado's recently adopted Donor-Conceived Persons Protection Act makes several important changes starting January 1, 2025 (enforcement begins July 1, 2025). For full details on how the rules will be implemented, see Colorado’s official regulations here:https://cdphe.colorado.gov/gamete-bank/rules-regulations
Xytex is in the process of obtaining a permit to ship to Colorado under the new legislation.
In the interim, Xytex may continue to ship to Colorado under the following circumstances:
Sperm collected prior to January 1, 2025 may still be provided to recipients in Colorado.
If you have any more questions concerning Colorado compiance for a specific donor, please call our Client Relations team at 706.733.0130. We are happy to assist you.
The process of becoming a sperm donor begins with in-depth screening. The health and medical history of our donors are extremely important, and every candidate must complete a thorough multi-step evaluation.
Candidates complete a medical history questionnaire, provide family medical history, and submit a semen sample for analysis. A Donor Coordinator conducts an in-depth interview and verifies education and background information.
Candidates also undergo a psychological assessment, laboratory testing, and a targeted physical exam. Throughout active participation in the program, donors continue to be monitored through periodic bloodwork, physical exams, and updated medical history reviews to help ensure continued health and program eligibility.
Xytex is committed to monitoring donor health throughout active participation in our program. Donors undergo periodic bloodwork, physical exams, and updated medical history reviews to help ensure continued health and program eligibility.
If Xytex becomes aware of clinically significant updated medical or genetic information, we may share that information with the client and/or the client’s healthcare provider. Because Xytex is not a medical provider and cannot offer medical advice, we strongly encourage clients to consult their healthcare provider or a genetic counselor regarding any updated medical or genetic information.
Yes. Xytex conducts comprehensive laboratory testing and physical exams on all donors to screen for infectious diseases and assess overall health. This includes testing for HIV, hepatitis B and C, syphilis, chlamydia, gonorrhea, CMV, and other required infectious disease markers.
In addition to infectious disease testing, all donors undergo genetic screening to identify carrier status for hundreds of inherited conditions, helping intended parents make more informed decisions.
Screening is the process of evaluating a donor for potential risk factors or indicators of infection based on medical history, questionnaires, and preliminary assessments. Testing involves laboratory analysis of biological specimens, such as blood, urine, or semen, to determine the presence of a specific infectious agent, such as a bacterium or virus.
Cryopreservation allows Xytex to safely store donor sperm until it is needed, making it possible to maintain our inventory and ship specimens to clients and clinics we serve.
Freezing also preserves sperm viability for extended periods. Once thawed, cryopreserved sperm can be as fertile as fresh sperm.
In addition, cryopreservation allows for a required quarantine period and repeat infectious disease testing in accordance with FDA regulations. This process helps ensure donor safety and specimen quality before vials are released for use.
With proper storage and temperature maintenance, cryopreserved sperm can remain viable for many years.
Comparing human births resulting from thawed semen to non-assisted pregnancies shows no difference in the rate of birth defects or miscarriage.
Cytomegalovirus (CMV) is a common virus that infects approximately 70% of persons in the United States by age 45 and more than 90% by age 80. In most cases, initial infection results in no symptoms, though some people experience a mild illness, similar to the flu or mononucleosis.? After the initial infection, the virus remains dormant (latent) in the body. Reactivation of infection typically occurs in persons with compromised immune systems.
If a woman who has never been exposed to CMV becomes infected with the virus during pregnancy, there is a 40% risk of fetal infection. In contrast, the risk of fetal infection is only 1% in women with previous CMV exposure. Fetal infection with CMV can result in miscarriage and serious developmental defects in approximately 10% of cases where primary infection occurs during the first 14 weeks of pregnancy.
Xytex tests all donors for CMV and includes each donor’s status in his profile. CMV status is based on testing blood for antibodies (IgG and IgM) to the virus. CMV-negative donors have no IgG or IgM antibodies. CMV-positive donors have IgG antibodies that persist for life, but the pattern of antibodies determines whether infection is latent (inactive) or active. Xytex does not accept sperm from donors whose test results suggest active or recent CMV infection (IgM-positive). Sperm from donors with latent infection (IgG-positive, IgM-negative) is considered to be safe.
Knowing your CMV status can help navigate your fertility journey. While it might seem reasonable to accept only CMV-negative donors, such a restriction would reduce the donor pool by more than half, leaving women with fewer choices. Xytex encourages clients to discuss CMV with their healthcare providers, who may recommend CMV testing. Providers often recommend that CMV-negative patients use sperm from CMV-negative donors.
Xytex relies on clients to report all births resulting from donor sperm use. Births should be submitted through your Xytex website account portal.
Timely birth reporting is essential to:
Maintain accurate tracking of family units per donor
Ensure continued access to the donor for clients building genetically related families, pending vial availability
Allow ongoing access to the donor’s profile and pertinent donor updates, such as medical or genetic information
Uphold the integrity, safety, and compliance of our donor program
Your cooperation helps protect donor-conceived children, supports responsible family planning, and strengthens the transparency and long-term success of the donor community.
We have made it easier than ever to manage your vial shipments directly from your Xytex Client Portal.
To get started:
1. Log in to your Client Portal at xytex.com.
2. Navigate to the My Orders tab.
3. There, you will see a list of your stored vials.
4. Simply select the vials you wish to ship, choose the destination, and confirm the shipment details.
5. Submit your request, and our team will take care of the rest!
This feature allows you to schedule shipments at your convenience—anytime, from anywhere.
Need help or have questions?
Our Customer Relations Team is ready to assist you.
Email: info@xytex.com
Call: 706-733-0130 or 1-800-277-3210
We are here to make the process smooth and stress-free.
ART vials are often used in IVF (in vitro fertilization) – sperm and egg are combined in a petri dish for fertilization.
An unwashed vial is frozen in its most natural state, allowing sperm to remain in its natural seminal fluid. Unwashed vials are used for ICI (intracervical insemination) – sperm enters through the cervix, much like in sexual intercourse.
A washed vial separates the sperm from its natural seminal fluid and is frozen in preserving fluid. Washed vials are used for IUI (intrauterine insemination). While we offer washed vials prepared for IUI treatment, we also offer unwashed vials, which are suitable for IUI, but require washing by the inseminating clinic.
*Please consult your Clinic for the appropriate vial type for your procedure.
Please also see this helpful video!
We are thrilled to partner with CapexMD,PatientFi and Future Family for financing to clients in the United States. With an easy process and competitive rates, finances don’t have to be an obstacle to achieving your dream of a family.
Some of the many advances of financing:
First, create an account and browse through our catalog of sperm donors. With our interactive features, you can view child and adult photos and gain insight from donors’ personal essays. When narrowing your search, we urge you to choose several of your top picks and rank them in order of preference.
When you’re ready, give us a call, and we will check availability of your top picks, making every effort to secure your first-choice. However, due to normal fluctuations in our inventory, this is not always possible. If you'd like to use the same donor for future children, we recommend buying additional vials during your initial purchase.
We also recommend consulting your healthcare provider when choosing a donor. They will be able to help you navigate things like expected day of ovulation and the number and type of vials needed for your procedure. We strongly recommend planning to have your vials delivered a day or two prior to ovulation.
Xytex is not able to facilitate the transfer of ownership of your vials to a third party. Xytex has a strict policy fprofibiting this type of transfer, as Xytex cannot guarantee the quality or integrity of the vials once shipped from our facility or another designated storage facility. In furtherance of this policy, clients complete a service agreement that states they are purchasing the vials for their own use or use by a partner and are not permitted to transfer them to any other entities. By following these policies, Xytex can maintain vial safety, compliance, international family limits and properly observe applicable laws.
Xytex ships donor specimens directly to your home residence, offering greater flexibility and added privacy for your fertility journey. However, it’s important to be aware that state laws vary regarding at-home insemination and legal parentage.
Some states require insemination to be performed only by a licensed physician. At-home insemination may not be legally recognized in those states.
In certain states, a husband must provide written consent prior to insemination for his name to appear on the birth certificate.
Other states may require proof of insemination with anonymous donor sperm for the recipient’s partner to be listed as a legal parent.
We strongly recommend consulting with your healthcare provider or legal advisor to ensure that at-home insemination is permitted and properly documented under your state’s regulations.
Home delivery is available in New York only with additional documentation completed by your licensed healthcare provider. Please review your state’s requirements before proceeding with your order.
Orders can be placed online and shipped directly to your residence for convenience and privacy.
A refundable tank deposit of $875 is required for all home deliveries.
An unwashed vial is frozen in its most natural state, allowing sperm to remain in its natural seminal fluid. A washed vial separates the sperm from its natural seminal fluid and is frozen in a preserving fluid. Removing seminal fluid helps minimize cramping that can result from prostaglandins, the hormones that cause the uterus to contract.
Washed vials should be used in IUI procedures, as unwashed vials injected into the uterus can cause cramping. In addition to being extremely painful, it will most likely result in the loss of injected sperm. Both washed and unwashed samples can be used for ICI or intracervical inseminations. ART samples are processed in exactly the same way, with the only difference being the minimum number of motile cells.
Both ICI and IUI vials are suitable for at-home vaginal insemination, and no additional preparation is needed. There are different volumes and cell numbers associated with each vial type, but these are in reference to the pre-purchase processing that occurs in our laboratory. Please see our Quality Commitment (https://www.xytex.com/about-xytex/quality-commitment/) for additional helpful information. *IVF vials are not intended nor recommended for at-home vaginal inseminations.
The number of vials needed varies based on your treatment plan and personal fertility journey. While it may not take four vials, national averages suggest 3–4 insemination cycles per successful pregnancy.
If you hope to have multiple children using the same donor, or want the option of future siblings, planning ahead is important. Donor inventory can sell out, and purchasing additional vials in advance is the only way to help ensure future availability.
Xytex offers complimentary storage and buyback options for qualifying vial purchases. Please contact our Client Relations team for current storage programs and details.
You or your health care provider can place an order by calling our Client Relations team at 706-733-0130. We also offer online ordering for some donors*. If online ordering is an option, it will appear at the bottom of a donor's profile. Shipments will only be sent once your health care provider signs our Supply Agreement form. *online ordering applies to US sales only
Please see the Xytex Forms page, specifically:
Donor Sperm Services Agreement
Shipping Agreement
See Also:
How To Sign My Docusign
Xytex understands that shipping to an alternate location may be desirable in certain circumstances. You may download the “Homeship” form (“Authorization for Release of Direct to Clients Shipments”) from the Xytex Forms page. Xytex recommends that clients and physicians become familiar with the laws governing artificial insemination in their state of residence.
We accept wire transfers and all major credit cards.
Your order is shipped via FedEx Next Day or 2nd Day, depending on the option you select. Please note that orders are shipped Monday through Friday between 8:30 a.m. and 5 p.m. EST. Our Client Services Team is available during these business hours to assist you.
Holiday Shipping: Please Plan Ahead!
During holidays and periods of severe weather, shipments may experience delays. We encourage clients to plan ahead and review current shipping alerts on the FedEx website.
We recommend that you request your shipment to arrive at least three days prior to insemination. FedEx Priority Overnight shipping will arrive the next business day by 12 pm. FedEx Two-Day shipping will arrive the second business day by 12 pm.*
*Overnight shipping may be affected by weather or Federal Express equipment failure. To help ensure your vials arrive in time, please plan for your shipment to be delivered 3 days prior to your insemination
Holiday Shipping: Please Plan Ahead!
During holidays and periods of severe weather, shipments may experience delays. We encourage clients to plan ahead and review current shipping alerts on the FedEx website.
Each vial arrives frozen in a screw-cap unit that is clipped to a metal support rod (a cane) to aid removal from the refrigerated tank (dry shipper). The tank is cooled with liquid nitrogen trapped in spongy material to prevent spillage, hence the name dry shipper. Each tank is shipped in a cardboard box which includes a packing slip with the Summary of Records (required by the FDA), thawing instructions, a letter from our Medical Director, a return shipping label and applicable invoices.
Please Plan Ahead! Due to heavy shipping volume, your order may be delayed. Visit the FedEx website to see how your shipment may be affected: https://www.fedex.com/en-us/service-alerts.html
Once you have selected the perfect donor, simply place your order. The vials will be shipped to your healthcare provider’s office in a sealed, refrigerated tank that will preserve your sample(s) for up to seven days. Two-day delivery options are available.
Holiday Shipping: Please Plan Ahead!
During holidays and periods of severe weather, shipments may experience delays. We encourage clients to plan ahead and review current shipping alerts on the FedEx website.
If your vials are being stored at Xytex or CANAM:
Xytex pemits a donors swap for a fee of $850 within 90 days of your initial purchase. We do not offer refunds on purchases as indicated in the Donor Sperm Services Agreement.
Once vials have left Xytex or an approved storage facility, they are ineligible for returns or exchanges.
The easiest way to ensure access to the same donor for future inseminations is to buy additional vials during your initial purchase. You can request to store them at our facility until needed for treatment.
If you plan to use the same donor for multiple insemination cycles or hope to have future siblings, storing additional vials with Xytex can help preserve your options. Donor inventory may sell out, and purchasing vials in advance is the best way to help ensure future availability.
Xytex offers complimentary storage for clients who plan ahead:
Once pregnant, you may choose to continue storage for future sibling planning or take advantage of the Xytex 50% Vial Buyback Program
Sign in to “My Account” and visit the Birth Report tab.
Since 1975, we have provided the expertise your patients need to fulfill their dreams of starting or growing a family. We let your patients choose from the industry’s most selective, most tested, and most successful donors.
Selective
Our donors are chosen with your patient and her future family in mind. Since January 2017, all donors have endured a rigorous screening process, which includes personality and behavioral evaluations.
Tested
We evaluate all donors for hereditary conditions using an extensive medical history questionnaire and carrier testing for genetic conditions.
Successful
Our donors have a minimum 12.5 million motile sperm per 0.5 mL in unwashed vials and 10.0 mL motile sperm per 0.5 mL in washed vials.
To view a current list of licenses, registrations and certifications, please visit our Licenses page.
We also adhere to the regulations regarding importation of products by the governments of Switzerland, Australia, and the United Kingdom (HFEA), as well as Health Canada, a federal governing board of Canada.
We comply with expectations published by the FDA in regards to Human Cells, Tissues, and Cellular and Tissue-Based Products (21 CFR Part 1271).
While we are willing to send donor specimens to any address specified on a client’s order form, regardless of the shipment's destination, we require clients to be under the care of a healthcare provider.
You must sign an Authorization to Ship to an Alternate Location form (located on the Xytex Forms page) before having any specimens shipped directly to the patient.
You want someone to care for your patients with compassion, support, and expert guidance. We offer an empowering experience, providing them with the best chance of conceiving a healthy baby. With Xytex, you get a partnership based on shared goals. It’s more than a transaction.
To start a partnership and establish a Physician Account, we ask that you complete a Supply Agreement form (located on the Xytex Forms page) which will allow you to designate the party responsible for paying for services – the clinic or the patient. Orders may be placed by the health care provider or clinic employees, but all orders will be confimed with the clinic prior to shipment.
We conduct laboratory testing and physical exams on all of our donors to assess their overall health. Additionally, we conduct genetic testing on all of our donors to help your patients confidently choose their family. An extensive list of donor testing can be viewed here.
During active participation in the program—those who regularly provide samples of blood, semen and urine—undergo a physical exam and a blood draw every six months.
Our screening and testing complies with government licensing agencies and is consistent with guidelines established by the FDA. Additionally, the United States Food and Drug Administration has regulations (21 CFR Part 1271) for screening and testing for specific sexually transmitted infections (STI). In addition to STIs, the state of New York and several organizations expect screening and testing for a few genetic conditions.
CMV is a common virus that infects 70% of persons in the United States by the age of 45 and more than 90% by the age of 80. In most cases, initial infection results in no symptoms, though some people experience a mild illness, similar to the flu or mononucleosis.? After the initial infection, the virus remains dormant (latent) in the body.? Reactivation of infection typically occurs in persons with compromised immune systems.
If a woman who has never been exposed to CMV becomes infected with the virus during pregnancy, there is a 40% risk of fetal infection.? In contrast, the risk of fetal infection is only 1% in women with previous CMV exposure. Fetal infection with CMV can result in miscarriage and serious developmental defects in 10% of cases where primary infection occurs during the first 14 weeks of pregnancy.
Approximately 1% of newborns in the United States are infected with CMV.? This is most often a result of primary maternal infection or maternal reactivation.?Congenital CMV infection may result in significant psychomotor, hearing, ocular, or dental abnormalities.
Tests for CMV antibodies can distinguish between current (recent) infection and latent infection. Individuals with current or recent infection have IgM antibodies in their blood. After an acute infection has resolved, IgM antibodies disappear; however, IgG antibodies persist indefinitely.
Xytex tests donors for CMV antibodies at least every six (6) months. Approximately 60% of Xytex donors are IgG-positive. Sperm from IgM-positive donors is not accepted.
We encourage you to discuss CMV with your patients. You are best suited and qualified to explain this issue and provide guidance. If you recommend using a CMV-negative donor, please ask your patient to call Xytex at 1-706-733-0130 or email info@xytex.com to confirm the donor's CMV status before placing an order.
Each vial arrives frozen in a screw-cap unit clipped to a metal support rod (a cane) to aid removal from the refrigerated tank (dry shipper). The tank is cooled with liquid nitrogen trapped in spongy material to prevent spillage, hence the name dry shipper. Each tank is shipped in a cardboard box. The shipment includes a packing slip with the Summary of Records (required by the FDA), thawing instructions, a letter from our Medical Director, a return shipping label, and applicable invoices.
We arrange for pickup of the tank on the eighth day after shipping from our facility. The tank should be sealed in the original shipping box and the return label applied to the outside surface of the box.
A daily rental fee of $40 applies to any tank kept beyond the pickup date. Given advance notice, we will work with your office to alleviate extenuating circumstances. We hold the health care provider and/or clinic financially responsible, not the patient, for any unreturned or damaged tank.
While Xytex may from time to time share updated clinically significant medical and/or genetic information with Client and Client's Healthcare Provider, it is up to Client, prior to using any Specimens obtained from Xytex, to contact: (I) Client's Healthcare Provider; and (II) Xytex, for any such updated information of which Xytex may become aware.
It is up to the Client to check the Donor's profile on the website for updated medical information. Client acknowledges and agrees that under some circumstances, Xytex may have shared such updated information only wtih Client's Healthcare Provider, in which event, whether or not Client would be informed of such updated information would be entirely dependent upon Client's contacting Client's Healthcase Provider and receiving such updated information.
Although Xytex is not obligated hereunder (or otherwise) to disclose or share with Client or Client's Healthcare Provider any updated clinically significant medical and/or genetic information, in the event Xytex does share any such updated information, an experienced genetics counselor should be consulted to advise Client as to its potential significance. Xytex is not a medical provider, and cannot provide medical advice.
Many genetic conditions have an autosomal recessive pattern of inheritance. To be autosomal recessive, both copies of the gene must be mutated (altered) in order to cause the condition. If only one copy is mutated, a person is considered to be a carrier of the condition but does not have the actual condition.
Help, My Sperm Donor Is A Carrier Of A Genetic Disease
Video by Jamie K. Dokson, ScM, LCGC(Licensed Certified Genetic Counselor)
We perform carrier testing on our donors to help reduce the risk of offspring inheriting common autosomal recessive conditions. Each donor’s profile includes a list of his genetic conditions, along with the results for which he was tested.*
*Genetic testing has changed over time, and some donors may have been tested for fewer conditions and with different methodologies. Incoming Xytex donors now undergo comprehensive carrier screening, covering hundreds of genes, including those recommended by the American College of Obstetricians and Gynecologists (ACOG) and the American College of Medical Genetics (ACMG).
Negative genetic testing only reduces the possibility that a donor is a carrier of a particular condition.
While we do accept donors who are found to be carriers of genetic conditions, to purchase sperm of a donor known to carry a genetic condition, a client must sign a waiver stating her understanding of the associated risks.
Additionally, if a female is a known carrier of a specific genetic condition, we will provide a copy of the donor’s test reports so that you can review this information with your health care provider and genetic counselor and make the most educated decision with regards to the health of your potential offspring.
It is estimated that 1 in 100 children are born with a genetic condition. The incidence of genetic conditions varies among ethnic groups. For example, Sickle Cell disease is more common among persons of African ancestry than Caucasians of European descent.
Xytex continuously updates its carrier screening panels to cover hundreds of genetic conditions, increasing options and reducing genetic risks. However, if you are a carrier of a genetic condition for which a donor was not tested, we can attempt to contact the donor to request additional carrier testing. While we strive to accommodate these requests, we cannot guarantee that the donor will agree to further testing. Please email info@xytex.com or call 1-706-733-0130 for additional information.
Sequencing of a gene involves reading a gene from beginning to end and comparing the code to a database of known normal and abnormal (pathologic) mutations. This method of genetic testing is more extensive. A negative result from sequencing reduces the likelihood of carrier status more than targeted mutation analysis, which only detects a few of the most common mutations of a particular gene. Genetic testing has changed over time, and some donors may have been tested for fewer conditions and with different methodologies. Men who joined our donor program since January 2019 have undergone comprehensive carrier testing of hundreds of conditions using next-generation sequencing, providing detailed genetic insights.
To initiate a home shipment, Xytex clients must complete the required Home Shipment Authorization forms and Genetic Waivers through DocuSign. These documents ensure that clients understand the process and acknowledge the associated considerations when choosing to proceed with at-home insemination.
As of our current policy, Xytex no longer requires the signature of a licensed medical professional to approve at-home inseminations for most U.S. residents. However, clients residing in the state of New York are subject to additional state regulations and must obtain written approval from their licensed physician before vials can be shipped to their home.
Please note that home shipments are available to U.S. clients only at this time. For assistance completing the necessary documentation or determining your eligibility, our Client Services Team is available to guide you through the process.
*Genetic waiver necessary only if the donor is a carrier of a genetic condition.
We have made it easier than ever to manage your vial shipments directly from your Xytex Client Portal.
To get started:
1. Log in to your Client Portal at xytex.com.
2. Navigate to the My Orders tab.
3. There, you will see a list of your stored vials.
4. Simply select the vials you wish to ship, choose the destination, and confirm the shipment details.
5. Submit your request, and our team will take care of the rest!
This feature allows you to schedule shipments at your convenience—anytime, from anywhere.
Need help or have questions?
Our Customer Relations Team is ready to assist you.
Email: info@xytex.com
Call: 706-733-0130 or 1-800-277-3210
We are here to make the process smooth and stress-free.
Understanding Vial Types for At-Home Insemination
At-home vaginal insemination may be performed using either IUI or ICI vials. It is important to understand the differences:
IUI (Intrauterine Insemination) vials are washed, meaning seminal fluid and non-motile sperm have been removed in our lab. These vials are processed for direct placement into the uterus but may also be used for vaginal insemination at home if advised by your provider.
ICI (Intracervical Insemination) vials are unwashed, meaning they contain the full ejaculate, including seminal plasma. These are generally used for vaginal or cervical insemination.
Each vial type differs in volume and motile sperm count due to the lab processing involved. For this reason, we strongly recommend that you consult with your healthcare provider before purchasing, to ensure the selected vial type aligns with your health history, insemination method, and overall fertility plan. Your provider can help you make the most informed decision based on your goals and comfort with at-home procedures.
Please Note: IVF (ART) vials are intended for use in assisted reproductive technologies such as IVF and are not recommended or approved for at-home vaginal insemination.
Important Shipping Policy
Vials shipped for at-home insemination are not eligible for return, replacement, or a Quality Commitment Report. Once shipped, all sales are considered final.
Cost and Shipping Information for At-Home Insemination
When ordering vials for home insemination, clients are responsible for the cost of the vial(s) and shipping fees, which vary based on destination and delivery timeframe.
A refundable tank deposit of $875 is also required. This deposit covers the use of a liquid nitrogen tank that protects the vial(s) during transit. Once the tank is returned to Xytex in good condition, your deposit will be refunded within 8–10 business days of its arrival back at our facility.
Vials shipped in our cryogenic tanks are guaranteed to maintain quality for up to 7 days from the date of shipment. Once the tank is opened, vials must be used within 24 hours to ensure optimal viability.
If you have questions about timing or tank handling, our Client Relations team is here to help guide you through the process.
If you're not ready to use your vials immediately, Xytex offers secure long-term storage options at our FDA-registered facilities. Storing your vials with us ensures they are maintained under strict cryogenic conditions, preserving their quality until you’re ready to proceed with treatment.
You can purchase vials now to reserve inventory from your selected donor and store them at Xytex for as long as needed. We offer flexible billing options for storage—monthly, quarterly, or annually—so you can choose what best suits your needs and planning. Our Client Relations Team is here to provide personalized support, whether you need help managing your storage account, updating billing preferences, or coordinating a shipment when the time is right. We're committed to supporting you every step of the way.
This flexible option provides peace of mind and helps you plan ahead with confidence.
How long will my vials remain frozen?
Your vials will remain safely frozen in the cryogenic shipping tank for up to 7 days from the date of shipment. The tank is pre-filled with liquid nitrogen to maintain the extremely low temperatures required to preserve the quality and viability of the sperm during transport and temporary storage.
We recommend that the tank remain closed until you are ready to proceed with insemination. Once the tank is opened, the vials should be used within 24 hours to ensure the best possible outcome.
If you anticipate any delay in using your vials or have questions about timing, please contact our Client Relations team—we're happy to help you plan accordingly.
No. Vials must remain in the liquid nitrogen shipping tank until you are ready to use them. Standard household freezers do not reach the temperatures required to safely preserve sperm and can damage the vial contents. For best results, keep the tank sealed and follow usage instructions provided.
What supplies do I need for home insemination?
At-home insemination can be a simple and empowering option for many families. To help you prepare, we’ve outlined the basic supplies you’ll need for the process:
Sperm Vial
You’ll receive your selected donor sperm vial—either IUI (washed) or ICI (unwashed)—based on your treatment plan and provider recommendation. Be sure to confirm with your healthcare provider which vial type is best suited for your needs.
Sterile Syringe
A sterile 1 mL syringe is included with your shipment. This is used to transfer the thawed sperm for vaginal insemination. If you prefer or require a different style of syringe, speak with your provider before your shipment date.
Disposable Gloves
Using gloves can help maintain a clean and hygienic environment during the insemination process.
A Comfortable, Quiet Space
You’ll want a clean and private area where you can lie down for 15 to 30 minutes after insemination to allow sperm the best chance to reach the cervix.
A Timer or Clock
Keeping track of how long you rest after the insemination can help you stay relaxed and consistent with your timing.
Helpful Reminders:
Keep the shipping tank sealed until you're ready to proceed. Once opened, the vial should be used within 24 hours.
Do not attempt to store the vial in a household freezer. The vial must remain in the liquid nitrogen tank until use.
If you have any questions about the process, our Client Relations team is here to support you.
Your shipment from Xytex will contain the following items:
One needle-free insemination syringe for each vial included in your order, designed for ease of use and comfort.
Comprehensive vial thaw instructions to help you properly prepare the specimen for insemination, ensuring optimal viability.
Please note that while we provide the necessary materials and instructions for insemination, it is important to follow the guidance of your healthcare provider or fertility specialist regarding your specific treatment plan and insemination timing. If you have any questions or concerns about the process, do not hesitate to reach out to your clinician for personalized support.
We understand that timing of insemination is one of the most important factors in achieving a successful pregnancy. Because each person’s cycle and fertility journey is unique, Xytex strongly encourages clients to consult with their healthcare provider or fertility specialist to determine the optimal time for insemination based on ovulation tracking and personal medical history.
For at-home insemination, your provider may recommend using ovulation predictor kits or other cycle-tracking tools to identify your most fertile window. In most cases, insemination is advised to occur within 24 hours of a positive ovulation test.
Additionally, many healthcare professionals recommend a second insemination within 24 hours of the first to increase the likelihood of conception. Be sure to discuss this option with your provider to determine what’s best for you.
If you are working with a clinic, your care team will schedule insemination (IUI or IVF) based on monitored ovulation or hormonal triggers.
At Xytex, we’re here to support you every step of the way and encourage you to reach out to our Client Relations Team for any assistance or to coordinate the timing of your shipment.
For individuals with no known fertility concerns, home insemination has an average success rate of 10–15% per cycle. This is similar to the natural conception rate through unassisted intercourse. It’s important to understand that conception is often not immediate—many individuals and couples may require multiple cycles before achieving a successful pregnancy.
Several factors can influence your chances of success with home insemination, including:
Age of the person trying to conceive
Timing of the insemination in relation to ovulation
Proper thawing/handling
Underlying medical conditions or reproductive history
While home insemination can be a convenient and accessible option for many, it’s not the right fit for everyone. That’s why Xytex strongly recommends consulting with your healthcare provider before beginning. A clinician can help assess your reproductive health, guide you on timing, and ensure that at-home insemination is a medically appropriate and safe option for your individual circumstances.
Please see our complete Quality Commitment here:
https://www.xytex.com/about-xytex/quality-commitment/
There are no refunds for approved quality reports. An approved quality report does not equate to cash value. Xytex will replace the vial for a vial of equal value or place a credit on the client account for future use.
